Adult Stem Cell Awareness

April 22, 2008

Cord Blood Clinical Trials

Filed under: adult stem cell awareness,Real Hope — chelseaz @ 2:41 pm

More human patients will be treated with “adult” stem cells:

DURHAM, NC–( Marketwire – April 16, 2008 ) – Aldagen, Inc. today announced that the first patient has been treated in a Phase III clinical trial for ALD-101. Aldagen is developing ALD-101 to improve cord blood transplants used to treat inherited metabolic diseases in pediatric patients. ALD-101 is a population of adult stem cells isolated from cord blood using Aldagen’s proprietary technology. The company commenced the Phase III clinical trial of ALD-101 to evaluate its ability to accelerate neutrophil and platelet engraftment following cord blood transplantation in these patients.

40 pediatric patients with inherited metabolic diseases undergoing a cord blood transplant will be treated in the multi-site Phase III clinical study. The primary goal of the study is to determine if ALD-101 can accelerate the restoration of circulating platelets. A 24-patient Phase I/II study of ALD-101 was previously conducted and a statistically significant reduction in the time to platelet engraftment was observed in patients receiving ALD-101 as part of a cord blood transplant compared to patients who had received a cord blood transplant without ALD-101 in an earlier independent clinical trial.

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See my adult stem cell archive


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