Adult Stem Cell Awareness

March 30, 2009

A potential revolution in the treatment of tiniest heart patients

Filed under: adult stem cell awareness,Real Hope — benotafraid @ 1:49 pm

Having a child with a single ventricle heart, I’m always on the look-out for exciting advances in the field. This recent report from Pediatric Cardiology proposes the use of engineered autologous (made from one’s own cells) tissue as an alternative to heart transplantation and radical reconstructive surgeries for heart kids. This has been on the horizon for a long time, but now it’s appearing in field standard journals . . . “the future” is getting closer and closer every day.

Received: 4 February 2009  Accepted: 26 February 2009  Published online: 25 March 2009

Abstract:  Children with severe congenital malformations, such as single-ventricle anomalies, have a daunting prognosis. Heart transplantation would be a therapeutic option but is restricted due to a lack of suitable donor organs and, even in case of successful heart transplantation, lifelong immune suppression would frequently be associated with a number of serious side effects. As an alternative to heart transplantation and classical cardiac reconstructive surgery, tissue-engineered myocardium might become available to augment hypomorphic hearts and/or provide new muscle material for complex myocardial reconstruction. These potential applications of tissue engineered myocardium will, however, impose major challenges to cardiac tissue engineers as well as heart surgeons. This review will provide an overview of available cardiac tissue-engineering technologies, discuss limitations, and speculate on a potential application of tissue-engineered heart muscle in pediatric heart surgery.

And of course, adult stem cells and autologous tissues have turned out to be impressively effective for adult hearts, too: Improved exercise tolerance for angina patients, ASC heart failure trials, plus more – use our blog search button for “heart” and “cardiac”.

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1 Comment »

  1. […] this widget for your site! Adult Stem Cell AwarenessCures Can Be Found Act of 2009 March 31, 2009A potential revolution in the treatment of tiniest heart patients March 30, 2009Change is in the air March 29, 2009Scientists to Test Ability of Stem Cells to […]

    Pingback by A potential revolution in the treatment of tiniest heart patients « Adult Stem Cell Awareness « The Stem Cell Blog — April 1, 2009 @ 4:57 pm | Reply


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