Adult Stem Cell Awareness

September 22, 2011

Possible Stem Cell Treatment for the Unborn!

Filed under: adult stem cell awareness,alternative sources — chelseaz @ 10:58 pm

Up to 40 percent of premature births are caused by a rupture in the membrane surrounding the foetus, causing labor. Babies born before 24 weeks have a poor chance of survival while later babies are at higher risk of birth complications.

(L-R): Dr Anna David, Dr Adam Squires and Dr Che Connon who are working to create stem cell patches to prevent early birth.


Previous attempts to treat this problem have not been successful, but some UK researchers are hoping that they’ve finally found the answer. A team from the Reading school of pharmacy have successfully developed sac membrane in the lab using stem cells from placentas obtained after births and created a ‘repair’ patch designed to be placed over the rupture using keyhole surgery. Dr Che Connon, who published the findings in the journal Tissue Engineering, told the UK Daily Mail,

‘We were able to manipulate the cells to make a material that is almost the same as a woman’s natural membrane.

‘It is tough and we are confident it would do the job and hold a pregnancy in place.’

And Dr Anna David, a consultant obstetrician and expert in premature birth at University College of London Hospitals Trust, said:

‘If we could use these membranes then we would be able to preserve pregnancies and save women from losing their babies.

‘This would be particularly beneficial for women whose membranes rupture before 24 weeks as the chances of these babies surviving are not very high. Before 20 weeks their lungs are simply not viable.’

Using non-embryonic stem cells to help save unborn babies? Come on. It really doesn’t get more “pro-life” than that! Dr Connon believes human trials will start in two years’ time and the treatment could be introduced by 2016.

Photo via UK Daily Mail

June 7, 2011

Pioneering stem cell bandage receives approval for clinical trial

Filed under: adult stem cell awareness,alternative sources,Real Hope — chelseaz @ 6:56 pm

Good news:

Millions of people with knee injuries could benefit from a new type of stem cell bandage treatment if clinical trials are successful. The world’s first clinical trial for the treatment of patients with torn meniscal cartilage has received approval from the UK regulatory agency, the MHRA1, to commence.

The current treatment for the majority of tears is the removal of the meniscus, a procedure that often results in the early onset of osteoarthritis.

The Phase I trial, one of the first in the UK to be approved using stem cells, will treat meniscal tear patients with a cell bandage product, seeded with the patient’s own, expanded, stem cells.

The cell bandage, produced by Azellon Ltd, a University of Bristol spin-out company, is focused on the research, development and commercialisation of an adult autologous (patient’s own) stem cell technology which in vitro (tissue culture) has shown great promise for the healing of meniscal tears.

The trial is designed primarily to test the safety profile of Azellon’s cell bandage in ten meniscal tear patients, but some information on whether or not it works will also be obtained. The bandage, containing the patient’s own stem cells will be implanted in a simple surgical procedure using a specially designed instrument that helps to deliver the cells into the injured site as a first-line treatment in place of removal of the meniscus. Patients will be closely monitored for safety over a five-year follow-up period.

Professor Anthony Hollander, Chief Scientific Officer at Azellon Ltd and Head of the School of Cellular and Molecular Medicine at the University of Bristol, said: “The approval we have received from the MHRA is an important milestone in the development of stem cell therapies in the UK. These cells hold much scientific and medical promise but we can only know if they work or not by testing them out in clinical trials.”

read more

May 17, 2011

Interview With Man Cured of HIV by Adult Stem Cell Transplant

Filed under: adult stem cell awareness,alternative sources,Real Hope — chelseaz @ 8:56 am

Here’s another follow-up to a story I mentioned on my website a few years ago:

Timothy Ray Brown tested positive for HIV back in 1995, but has now entered scientific journals as the first man in world history to have that HIV virus completely eliminated from his body in what doctors call a “functional cure.”

Brown was living in Berlin, Germany back in 2007, dealing with HIV and leukemia, when scientists there gave him a bone marrow stem cell transplant that had astounding results.

“I quit taking my HIV medication the day that I got the transplant and haven’t had to take any since,” said Brown, who has been dubbed “The Berlin Patient” by the medical community.

Brown’s amazing progress continues to be monitored by doctors at San Francisco General Hospital and at the University of California at San Francisco medical center.

“I’m cured of HIV. I had HIV but I don’t anymore,” he said, using words that many in the scientific community are cautiously clinging to.

Read more – with video interview.

This is incredible – and accomplished using ethically derived stem cells. Pass it on!

Previous posts (from my website):
Did Adult Stem Cells Cure an AIDS Patient??
More on Possible Future Stem Cell Trials for AIDS Treatment

August 5, 2010

Marine Vet to Participate in First U.S. ASC Clinical Trial for SCI

Filed under: adult stem cell awareness,alternative sources — chelseaz @ 10:28 am

Many thanks to Dr. David Prentice for calling my attention to this awesome news!

TCA Cellular Therapy, LLC has enrolled its first patient to participate in the U.S. Food and Drug Administration (FDA) first adult stem cell clinical trial to treat spinal cord injuries. Enrollee and Marine Veteran, Matt Cole was paralyzed from the chest down in a 2005 insurgent attack in Iraq.

“Many spinal cord injury patients have no effective treatment available at this time,” stated Dr. Gutnisky. “I’m very encouraged by the results of the pre-clinical trials and anticipate this may become a significant therapy for these patients in the near future.”

Utilizing TCA Cellular’s proprietary therapy, a couple of thousand adult stem cells have been extracted from the patient’s own bone marrow, Mesenchymal Stem Cells have been separated, purified, multiplied to millions and will be infused into Cole’s spinal cord later this month.

This is great! Though it’s still a very early trial, researchers have had great success in the past few years using ASCs to restore some feeling and movement in patients with SCI: see here, here, here, here, here and here. And how nice that we’re starting out by helping one of our wounded service men! There actually is an Armed Forces Institute for Regenerative Medicine that, just a few years ago, received an $85 million Federal grant for orthopedic stem cell surgery for veterans injured in Iraq and Afghanistan. They have another trial in the works involving spray-on skin cells for burn victims.

Ironic that this comes within a week of the announcement that Geron was re-approved for the very first embryonic stem cell trial to treat spinal cord injury. Why do I have a feeling that, though the AP surprised us recently with a very favorable article on adult stem cell success, no mainstream media outlets will be reporting on this like they did the Geron trial?

AP Touts ADULT Stem Cell Research

Filed under: adult stem cell awareness,alternative sources — chelseaz @ 10:24 am

You know, after all its hype of embryonic stem cell research over the years, I can’t help but think that the MSM is a little frustrated that they have not been able to report on any actual benefits from these cells. Meanwhile the success of adult stem cells is getting harder for them to ignore. The headline: Adult stem cell research far ahead of embryonic. Umm…a little late to the party there, folks, but thanks for finally taking notice:

For all the emotional debate that began about a decade ago on allowing the use of embryonic stem cells, it’s adult stem cells that are in human testing today. An extensive review of stem cell projects and interviews with two dozen experts reveal a wide range of potential treatments.

Adult stem cells are being studied in people who suffer from multiple sclerosis, heart attacks and diabetes. Some early results suggest stem cells can help some patients avoid leg amputation. Recently, researchers reported that they restored vision to patients whose eyes were damaged by chemicals.

Apart from these efforts, transplants of adult stem cells have become a standard lifesaving therapy for perhaps hundreds of thousands of people with leukemia, lymphoma and other blood diseases.

“That’s really one of the great success stories of stem cell biology that gives us all hope,” says Dr. David Scadden of Harvard, who notes stem cells are also used to grow skin grafts.

“If we can recreate that success in other tissues, what can we possibly imagine for other people?”

Read more and do browse our archives for a lengthy list of ASCR therapeutic successes.

June 18, 2010

Blind Patients’ Sight Restored With Help from Their Own Stem Cells

Filed under: adult stem cell awareness,alternative sources — chelseaz @ 3:28 pm

Bloomberg reports:

Patients blinded in one or both eyes by chemical burns regained their vision after healthy stem cells were extracted from their eyes and reimplanted, according to a report by Italian researchers at a scientific meeting.

The tissue was drawn from the limbus, an area at the junction of the cornea and white part of the eye. It was grown on a fibrous tissue, then layered onto the damaged eyes. The cells grew into healthy corneal tissue, transforming disfigured, opaque eyes into functioning ones with normal appearance and color, said researchers led by Graziella Pellegrini of the University of Modena’s Center for Regenerative Medicine.

The stem-cell treatment restored sight to more than three- quarters of the 112 patients treated, Pellegrini said yesterday in a presentation at the International Society for Stem Cell Research meeting. The patients were followed for an average of three years and some for as long as a decade, Pellegrini said.

Read more

H/t FRC blog

May 26, 2010

New Disease Identified, Treated with Adult Stem Cells

Filed under: adult stem cell awareness,alternative sources — chelseaz @ 7:58 am

This is pretty amazing:

Researchers at the Queensland Institute of Medical Research (QIMR) and the Royal Brisbane Women’s Hospital have identified a previously undiagnosed condition and successfully treated it by performing an experimental stem cell transplant.

Having spent her late teenage years in and out of hospital Katie Pulling had almost given up hope. “It was very confusing and very daunting. I kept hearing the doctors say, ‘We don’t know what is wrong’, ‘We don’t know why you are so sick’,” said Katie, who lives in north-eastern NSW.

With no options left Katie agreed to an experimental stem cell transplant – a transplant which ultimately saved her life.

Read more!
(h/t FRC Blog)

November 28, 2009

Stem Cells Heal Lungs of Newborn Animals

Filed under: adult stem cell awareness,alternative sources — chelseaz @ 11:19 pm

Scientists are hopeful that this study (from Nov. 2009) may lead to new treatments for lungs of premature babies:

An international team of scientists led by Dr. Thébaud has demonstrated for the first time that stem cells protect and repair the lungs of newborn rats. “The really exciting thing that we discovered was that stem cells are like little factories, pumping out healing factors,” says Dr. Thébaud, an Alberta Heritage Foundation for Medical Research Clinical Scholar. “That healing liquid seems to boost the power of the healthy lung cells and helps them to repair the lungs.”

In this study, Thébaud’s team simulated the conditions of prematurity — giving the newborn rats oxygen. The scientists then took stem cells, derived from bone marrow, and injected them into the rats’ airways. Two weeks later, the rats treated with stem cells were able to run twice as far, and had better survival rates. When Thébaud’s team looked at the lungs, they found the stem cells had repaired the lungs, and prevented further damage.

Read more

November 19, 2009

ASCs Saved My Life Education & Awareness Campaign Launched

Filed under: adult stem cell awareness,alternative sources,Real Hope — chelseaz @ 11:09 pm

I did go to the launch of the Adult Stem Cells Saved My Life campaign last Saturday. Here is a local news story about the launch:

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It was very well done and the testimonies were encouraging as always. The event was held in Kansas City where over 1,500 adult stem cell transplants have taken place! How nice it is to actually see positive results in human patients! Shamefully an intellectually dishonest campaign of junk science and emotional manipulation has largely dismissed or ignored the benefits of adult stem cells and lead many to believe that our greatest hope for therapies and cures lies in research that requires the creation, use and destruction of tiny human beings (despite growing evidence to the contrary). This manipulation and misinformation is what lead Missouri voters to approve “Amendment 2” in 2006, creating a constitutional right to clone and kill human embryos in our State.

We were going to take our own video of the testimonies while we were there, but they already have a few very nicely done little videos that tell some of the patient’s stories. They are featured on the new website StemCellResearchFacts.org:

Laura Domingues has a spinal cord injury and is now starting to walk again with the help of Adult Stem Cells taken from her own nose. She’s working with Dr. Carlos Lima from Portugual who has been studying olfactory mucosa autografts in human spinal cord injury – you can see his pilot study here. Another patient of Dr. Lima has given her testimony several times as well, which you can see here. More on ASCs and SCI: here, here, here, here and here.

Little Joseph Davis was cured of sickle cell anemia with his little brother’s umbilical cord blood stem cells. These guys were super cute on Saturday. Joe’s little brother went up to the mike and told the audience, “I gave my brother my cord blood and now we can play together!” See this story on sibling cord blood transplantation for sickle cell and the Sickle Cell Information Center’s Bone Marrow and Cord Blood Stem Cell Transplant page for more.

Amy Daniels has had a near complete recovery from Scleroderma- a disease that causes the tissue in the skin, blood vessels, and muscles to harden. More on ASCs and Scleroderma here, here, here, here, and here – for starters.

We also heard from Doug Rice who was at end-stage heart failure and was not a candidate for transplant because of his diabetes. Doug was at death’s door, and preparing for it, until he met with scientists (from Israel and Bangkok) who isolated stem cells from his blood, cultivated them and implanted them into his coronary artery. According to Doug the effects were immediate with his heart increasing to 41 percent efficiency from 11 percent before the procedure. After seeing this man’s testimony and meeting and talking with him for a few minutes I can tell you this man does not look like anyone in the advanced stages of heart failure! Watch video of Doug telling his story here: part 1 and part 2 (Windows media). And yes, there is more on ASCs and heart treatment: here, here, here, here, here, here, here, here, here)

November 12, 2009

Cord Blood Reverses Cerebral Palsy in Colorado Girl

Filed under: adult stem cell awareness,alternative sources — chelseaz @ 8:20 pm

FoxNews reports:

On May 28, 2008, at the age of 2, Chloe received a 15-minute re-infusion of her stem cells.

“The doctor is really cautious about what she tells patients,” Jenny Levine (Chloe’s mother) said. “She didn’t have a whole lot of results coming in. The best case scenario, we’d see signs of improvement in six months to a year.”

Within four days, her parents saw a noticeable difference, although Kurtzberg said most kids show benefits three to nine months later.

The rigidity on Chloe’s right side loosened up and her speech started to improve. She was able to ride her toy tractor, which in the past had been too difficult for her to pedal.

“Her life is completely normal, she doesn’t drag her right foot, she can use her right hand,” Jenny Levine said. “She rides a bike, a scooter…we’re taking her skiing this year. She’s fabulous.”

At this time, (Dr. Joanne) Kurtzberg (a professor of pediatrics and pathology at Duke University) said she does not know how long the effects of cord blood will last on kids like Chloe, but if there is a good chance it will be “durable and last indefinitely.” This is essential, since most babies have enough cells for only one infusion.

Read more

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